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. 2023 Feb 14;15:1094778. doi: 10.3389/fnagi.2023.1094778

Table 1.

Baseline characteristics of the study participants.

Characteristics at initial visit Total (n = 938,635) PD-free at follow-up (n = 928,711) Incident PD at follow-up (n = 9,924)
Sex
Male (%) 475,609 471,207 (50.7%) 4,402 (44.4%)
Female (%) 463,026 457,504 (49.3%) 5,522 (55.6%)
Age groups, y
≤50 155,240 154,895 (16.7%) 345 (3.5%)
51–55 216,621 215,862 (23.2%) 759 (7.7%)
56–60 169,606 168,432 (18.1%) 1,174 (11.8%)
61–65 138,092 136,329 (14.7%) 1,763 (17.8%)
66–70 121,046 118,542 (12.8%) 2,504 (25.2%)
71–75 77,919 75,890 (8.2%) 2,029 (20.5%)
76–80 38,910 37,890 (4.1%) 1,020 (10.3%)
81–85 15,687 15,407 (1.7%) 280 (2.8%)
≥86 5,514 5,464 (0.6%) 50 (0.5%)
Hypertension (%) 344,839 339,625 (36.6%) 5,214 (52.5%)
Diabetes (%) 97,162 95,514 (10.3%) 1,648 (16.6%)
Dyslipidemia (%) 139,135 137,049 (14.8%) 2,086 (21.0%)
Ischemic stroke (%) 33,408 32,576 (3.5%) 832 (8.4%)
Hemorrhagic stroke (%) 8,538 8,362 (0.9%) 176 (1.8%)
Ischemic heart disease (%) 92,466 53,126 (5.7%) 1,039 (10.5%)
Depression (%) 107,609 105,493 (11.36%) 2,116 (21.3%)
Osteoporosis (%) 199,675 196,332 (21.1%) 3,343 (33.7%)
Obesity (%) 340,780 337,065 (36.3%) 3,715 (37.4%)
Physical inactivity (%) 513,526 507,495 (54.7%) 6,031 (60.8%)
Heavy alcohol consumption (%) 100,300 99,374 (10.7%) 926 (9.3%)
Smoking
Never 672,659 664,801 (71.6%) 7,858 (79.2%)
Ex-smoker 86,394 85,671 (9.2%) 723 (7.3%)
Current smoker 179,582 178,239 (19.2%) 1,342 (13.5%)

PD, Parkinson’s disease.