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. 2023 Feb 14;14:1107639. doi: 10.3389/fimmu.2023.1107639

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Copyright © 2023 Guan, Mao, Tan, Liu, Zhang, Li, Liu, Wang, Cheng, Cui, He, Wang, Gao, Wang, Bian, Wu, Hou, Liang and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Neutralizing antibody (NtAb) geometric mean titers (GMT) of all collaborative calibration study samples across all participants. (A) Live virus neutralization assay (Neut), WT strain; (B) Neut assay, Delta variant; (C) Pseudovirus neutralization assay (PsN), WT strain; (D) PsN assay, Delta variant. Nine laboratories with experience in testing SARS-CoV-2 NtAbs participated in this collaborative calibration study. The Neut method was adopted by six laboratories, and the PsN method was adopted by four laboratories. In each laboratory, three independent and effective tests were performed on all samples using the WT and Delta strains, respectively. All laboratories returned results according to requirements.