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. 2023 May 4;8:14. Originally published 2023 Jan 10. [Version 2] doi: 10.12688/wellcomeopenres.18737.2

Table 3. Associations of Schistosoma diagnostics with visual-FGS.

Participant
Characteristics
Visual FGS
not detected
Visual FGS
detected
Crude OR P-
value *
Adjusted OR ** P-
value
Schistosoma diagnostics
(Reviewer 1)
n=303 n=165
Eggs on urine microscopy Not detected 287 (94.7) 151 (91.5) reference 0.3 reference 0.2
Detected 16 (5.3) 14 (8.5) 1.66 (0.73 – 3.74) 1.68 (0.74 – 3.81)
Circulating anodic antigen ~ Not detected 261 (86.1) 131 (80.4) reference 0.1 reference 0.1
Detected 42 (13.9) 32 (19.6) 1.52 (0.92 – 2.52) 1.49 (0.91 – 2.51)
Any positive genital PCR DNA not
detected
288 (95.1) 155 (93.9) reference 0.8 reference 0.7
DNA detected 15 (4.9) 10 (6.0) 1.24 (0.54 – 2.82) 1.27 (0.55 – 2.94)
Schistosoma Diagnostics
(Reviewer 2)
n=152 n=265
Eggs on urine microscopy †† Not detected 147 (96.7) 243 (91.7) reference 0.06 reference 0.07
Detected 5 (3.3) 22 (8.3) 2.65 (0.95 – 9.17) 2.65 (0.95 – 9.19)
Circulating anodic antigen ~ Not detected 131 (86.7) 215 (81.4) reference 0.2 reference 0.2
Detected 20 (13.3) 49 (18.6) 1.49 (0.85 – 2.62) 1.49 (0.85 – 2.63)
Any positive genital PCR DNA not
detected
146 (96.1) 248 (93.6) reference 0.3 reference 0.3
DNA detected 6 (3.9) 17 (6.4) 1.69 (0.64 – 4.33) 1.67 (0.64 – 4.36)

*Chi squared p-value unless otherwise noted

**Adjusted for age

†Likelihood ratio test p-value

Missing values not included in the table: ~ (n=2)

††Odds Ratios and p-values obtained through exact logistic regression in both crude and adjusted analyses