Table 3.

Association of weighted and unweighted genetic risk scores with log-transformed hsCRP in patients with type 2 diabetes

Variables		Log hsCRP
			Crude model		Adjusted model
	n	Mean±SD	β (SE)	F value	β (SE)	F value
Unweighted genetic risk score, per 1 point	2332	0.25±1.05	0.11 (0.01)*	75.54*	0.11 (0.01)*	39.05*
Tertile 1: 0~2	812	0.03±1.06	ref	33.14*	ref	36.12*
Tertile 2: 3~4	766	0.30±1.05	0.27 (0.05)*		0.23 (0.05)*
Tertile 3: >5	754	0.45±0.99	0.42 (0.05)*		0.42 (0.05)*
Weighted genetic risk score, per 1 point	2332	0.25±1.05	0.42 (0.05)*	74.72*	0.43 (0.04)*	40.76*
Tertile 1: 0~0.56	812	0.03±1.06	ref	32.83*	ref	37.4*
Tertile 2: 0.57~1.03	759	0.30±1.05	0.27 (0.05)*		0.24 (0.05)*
Tertile 3: >1.03	761	0.44±0.99	0.42 (0.05)*		0.39 (0.05)*

Multivariate model adjusting for covariates that satisfy the MR assumption 2.

*p<0.001.

hsCRP, high-sensitivity C-reactive protein.