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BMAL1 modulates the c‐Myc expression through ERK‐ and JNK‐dependent signaling pathway. (A) Inhibiting the MAPK pathway suppressed c‐Myc but increased E‐cadhrein expression in vitro using ERK1/2 (APExBIO PD98059, 10 μM) and JNK inhibitor (SP600125, 10 μM). (B) MAPK pathway inhibition markedly decreased the protein expression of c‐Myc. *p < 0.05, **p < 0.01 and ***p < 0.001.
