Table 2.

Univariate and multivariate cox analysis of 272 patients.

Parameters	Uni-HR	95% CI	P	Multi-HR	95% CI	P
Age	1.2	0.94-1.6	0.13
Gender	0.8	0.61-1	0.1
Smoking History	1.9	1.4-2.5	<0.0001	1.72	1.25-2.37	0.001
Anatomical type	1.3	1.2-1.5	<0.0001	1.95	1.42-2.68	<0.001
EGFR			0.15
Sensitive mutation	0.74	0.55-1.1	0.057
Resistance mutation	1.02	0.53-1.9	0.96
Bone metastasis	1.3	0.97-1.7	0.087	1.42	1.05-1.92	0.025
Brain metastasis	0.94	0.7-1.3	0.67
Liver metastasis	2.1	1.4-3	0.00012	1.52	0.99-2.34	0.056
NLR4	2.3	1.6-3.1	<0.0001	1.98	1.42-2.74	<0.001
PLR4	1.4	1-1.9	0.031
LMR4	0.59	0.44-0.8	0.001
LDH4	1.9	1.4-2.6	<0.0001	1.84	1.32-2.57	<0.001