Table 1.
Values for cardiovascular and other vital variables for six cats anesthetized with isoflurane after oral administration of gabapentin (100 mg cat−1) or empty capsules 2 h before starting MAC determination; cardiovascular and other vital variables were obtained after equilibration at the lowest FE′Iso when cats did not respond to tail clamping.
| Variables | Gabapentin treatment | Placebo treatment |
|---|---|---|
| PE′CO2 (mmHg) | 33 (30–39) | 34 (30–39) |
| SpO2 (%) | 100 (98–100) | 100 (100–100) |
| HR (beats minute−1) | 189 (119–217) | 187 (109–225) |
| SBP (mmHg) | 115 ± 23 | 120 ± 27 |
| T (°C) | 38.8 (38.7–39.2) | 38.9 (38.6–39.1) |
| FE′Iso (%) at extubation | 0.25 ± 0.05 | 0.59 ± 0.10* |
| TE (minutes) | 7 ± 4 | 6 ± 4 |
PE′CO2, end-tidal partial pressure of carbon dioxide; SpO2, arterial hemoglobin oxygen saturation percentage; HR, heart rate; SBP, systolic blood pressure by Doppler ultrasonic device; T, rectal temperature; FE′Iso, end-tidal isoflurane concentration; TE, time from discontinuation of isoflurane to extubation.
*Significant difference between two treatments (p < 0.05).