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Molecular efficacy of the TM5614 combination. (A) Cumulative incidences of a MR4.5 conversion by 48 weeks. Eleven patients (33.3% [95% confidence interval (CI), 18.0%–51.8%]) achieved MR4.5 during 48 weeks. The median time to MR4.5 was 8 weeks [95% CI, 4–24]. (B) BCR‐ABL IS % kinetics within 48 weeks. Boxes, 5–95 percentiles; horizontal bars, median; vertical brackets, ranges.
