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. 2022 Sep 23;12(4):4250–4258. doi: 10.1002/cam4.5292

FIGURE 4.

FIGURE 4

Cumulative incidences of MR4.5 conversion by 48 weeks according to the halving time at 8 weeks. Eight patients (80%) in the shorter halving time group achieved a MR4.5 during 48 weeks. The median time to MR4.5 was 6.07 weeks (95% confidence interval [CI], 4.00–8.00). Two patients (9%) in the longer halving time group achieved a MR4.5 during the 48‐week study period. The median time to a MR4.5 was not reached. Log‐rank test: p < 0.0001.