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Study design—outline.
EDSS: Expanded Disability Status Scale; TUG: Timed-Up and Go; T25FW: Timed 25-Foot Walk; 2MWT: 2-Minute Walk Test; MSWS-12: 12-item MS Walking Scale; MHI-5: 5-item Mental Health Inventory; MFIS-5: 5-item Modified Fatigue Index Scale; PES: Pain Effects Scale; BLCS: Bladder Control Scale; BWCS: Bowel Control Scale; WHODAS: WHO Disability Assessment Schedule; MRI: magnetic resonance imaging.
