Table 2.
Ablation study on the synthetic and real experiments. Bold-faced results highlight the best performing result. AUCs are listed for the experiments with real patient cohorts. The synthetic experiments list the accuracy values.
| Ablation study | Endometrial Cancer (AUC) | Breast Cancer (AUC) | Synthetic experiments (Acc.) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| POLE | Hist. | MMR | CNV | RI-RIII | RI-RII | RII-RIII | PMI1 | PF1 | CCI1 | NNI1 | |
| All networks | 0.98 | 0.98 | 0.97 | 0.97 | 0.73 | 0.68 | 0.56 | 93.6 | 99.7 | 98.9 | 86.7 |
|
| |||||||||||
| w/o Phenotype learning | 0.98 | 0.98 | 0.99 | 0.98 | 0.66 | 0.65 | 0.56 | 77.7 | 98.8 | 96.7 | 88.9 |
| w/o Neighborhood learning | 0.94 | 0.96 | 0.98 | 0.95 | 0.63 | 0.62 | 0.52 | 60.3 | 63.5 | 35.3 | 60.2 |
| w/o Area learning | 0.93 | 0.97 | 0.99 | 0.99 | 0.70 | 0.65 | 0.52 | 98.8 | 80.8 | 98.6 | 86.5 |