. Author manuscript; available in PMC: 2023 Feb 28.

Published in final edited form as: Brain Cogn. 2018 Dec 12;133:94–105. doi: 10.1016/j.bandc.2018.11.009

Table 3.

Stressor-induced increases in extracellular corticosterone by region and time

Stressor	Stressor duration	Delay: stressor onset to increase	Delay: stressor onset to peak	Region	Reference
Restraint	20	10^*	30^*	Hippocampus	Garrido et al. (2012)
Restraint	20	10^*	30^*	PFC	Garrido et al. (2012)
Predator	30	15^*	45^*	Hippocampus	Linthorst et al. (2000)
Forced swim	15	15^†	50^*	Hippocampus	Droste et al. (2008)
Forced swim	15	15	60^*	Caudate-putamen	Droste et al. (2008)
Footshock	1	15^*	60^*	mPFC	Dominguez et al. (2014)
Footshock	1	15^*	60^*	Dorsal hippocampus	Dominguez et al. (2014)
Footshock	1	15^*	60^*	Dorsal hippocampus	Dorey et al. (2012)
Forced swim	15	20	60^*	BLA	Bouchez et al. (2012)
Footshock	1	90^*	105^*	Ventral hippocampus	Dorey et al. (2012)

^*:

showed statistically significant increases in corticosterone from baseline at the indicated time-point; if not marked, appeared elevated from visual inspection but significance was not reported.

^†:

Based on Fig. 4. In Fig. 5, this increase appears evident at 5 min.

mPFC = medial prefrontal cortex, BLA = basolateral amygdala.