Fig. 6.
NIR-II fluorescence-guided surgery for colorectal peritoneal cancer. (a–c) Intraoperative white light, BLI and NIR-II imaging. (d, e) Primary tumour resection under NIR-II fluorescence guidance (d, T1), then complete resection of peritoneal metastases and abdominal residual tumour (e, T2, T3). (f) BLI imaging after surgery. (g, h) Pathological results of all resected tumours and immunohistochemical staining for CEACAM5. (i) Fluorescence intensity of all orthotopic tumours (n = 25) and peritoneal metastases (n = 15), subcutaneous tumours (n = 15). (j) TBR of orthotopic tumours, peritoneal metastases, and subcutaneous tumours.