Figure 5.

Heatmaps of differentially expressed proteins in the comparison between FRDA and CT (left), FRDA and ISO CT (middle), ISO CT and CT (right) neurons. The log₂(Fold Change) between the two groups analysed (FRDA/CT, FRDA/ISO CT or ISO CT/CT) is shown for each protein on the left side of the corresponding heatmap. For each comparison, the level of expression of identified proteins was represented also for the third group, allowing a direct comparison among all lines. Colour scale represents mean peak intensity of protein spectra in the log₂ scale. Exact values of mean peak intensities for each protein are indicated in the heatmaps (n = 2 for CT, n = 5 for FRDA, n = 3 for ISO CT).