Table 3.

Factors associated with progression-free survival

Characteristics	Univariate analysis			Multivariate Analysis
	HR	95% CI	P	aHR	95% CI	P	aHR	95% CI	P	aHR	95% CI	P
Age, years
<55	Ref.			Ref.			Ref.			Ref.
≥55	1.253	0.892–1.761	0.194	1.064	0.754–1.503	0.723	1.181	0.829–1.682	0.357	1.087	0.770–1.534	0.637
FIGO stage
I-II	Ref.			Ref.			Ref.			Ref.
III	2.644	1.281–5.457	0.009	2.151	1.027–4.506	0.042	2.022	0.961–4.253	0.063	2.112	1.006–4.433	0.048
IV	4.440	2.064–9.551	<0.001	3.177	1.442–7.000	0.004	3.208	1.454–7.076	0.004	3.283	1.484–7.264	0.003
Residual tumor after surgery
No gross	Ref.			Ref.			Ref.			Ref.
Gross	2.313	1.617–3.308	<0.001	1.898	1.311–2.747	0.001	1.954	1.355–2.817	<0.001	1.949	1.349–2.816	<0.001
GSN
Low	Ref.			Ref.
High	1.850	1.292–2.648	0.001	1.556	1.073–2.256	0.020
VCAN
Low	Ref.						Ref.
High	0.601	0.365–0.988	0.045				0.617	0.370–1.030	0.065
SND1
Low	Ref.									Ref.
High	0.607	0.355–1.040	0.069							0.789	0.454–1.372	0.401

Abbreviations: aHR, adjusted hazard ratio; CA-125, cancer antigen 125; CI, confidence interval; FIGO, International Federation of Gynecology and Obstetrics; HR, hazard ratio; Ref., reference.