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FAP expression in CCl4and Mdr2−/− fibrotic livers with/without FAP inhibition and effect of rhFAP/rmFAP on LX-2 HSCs and murine fibroblasts. (A–B), Transcript levels of fap. (C–D), Effect of treatment with rhFAP on LX2 HSCs activation and collagen gene expression. (E–F), Effect of treatment with rmFAP on NIH/3T3 fibroblast activation and collagen gene expression. Data in (A–F) are means ± standard error of the means (SEMs). Statistical analysis was performed as detailed in Figure 1.
