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Difference in methylation according to ICC values. The x-axis represents the mean difference in methylation relative to the ICC on the y-axis. Note that the shape is slight conical, with the mean difference in methylation decreasing as the ICC increases. This becomes slightly more visible when binning the ICC values by the poor (ICC < 0.5), moderate (0.5 ≤ ICC < 0.75), good (0.75 ≤ ICC < 0.9), and excellent (0.9 ≤ ICC) ICC classification, shown below.
