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. 2022 Dec 27;15(4):869–885. doi: 10.1016/j.jcmgh.2022.12.011

Table 3.

Hyper-stable Methylated Positions (ICC ≥0.9)

CGID Coordinate ICC P-valueICC P-adjustedICC DM P-valueDM P-adjustedDM Gene
cg04998153 chr1:101823331 0.990153046 2.24E−40 4.64E−38 0.002350766 .917048378 .960490142 LINC01307 (body)
cg06231783 chr11:1475048 0.990318642 1.53E−40 3.24E−38 −0.002016075 .913436831 .958698404 BRSK2 (body)
cg22113540 chr16:10125521 0.990357545 1.40E−40 2.98E−38 −0.005125811 .726564998 .852281861 GRIN2A (body)
cg04546413 chr19:29218101 0.992092045 1.64E−42 4.48E−40 −0.008758714 .737190388 .859028126
cg05896524 chr21:47604654 0.991011374 2.90E−41 6.71E−39 −0.00862793 .708898078 .841027778 C21orf56 (TSS1500)
cg20540428 chr3:73045686 0.990348581 1.43E−40 3.03E−38 −0.005080004 .778207203 .884339751 PPP4R2 (TSS1500)
cg22243260 chr3:126946036 0.991961418 2.37E−42 6.31E−40 −0.000283585 .989690923 .995366819
cg16885113 chr6:29648507 0.990173675 2.14E−40 4.44E−38 0.009565754 .695688826 .832438074
cg18280909 chr6:29723301 0.990760129 5.38E−41 1.21E−38 0.009797484 .631735087 .788308313
cg09271603 chrX:24482885 0.990091759 2.57E−40 5.29E−38 0.002551285 .901311297 .952513118 PDK3 (TSS1500)
cg08222221 chrX:139589617 0.990360759 1.39E−40 2.95E−38 −0.005243195 .737019022 .858927936

CGID, Illumina CpG identifier; Coordinate, Genomic coordinate of the CpG on the human genome (build hg19); DM, mean difference in percentage methylation; ICC, intraclass correclation coefficient; Gene, associated gene as well as the location in the gene; P-valueICC, P-value associated with the intraclass correlation coefficient; P-adjustedICC, Benjamini-Hochberg-adjusted P-value associated with the intraclass correlation coefficient; P-valueDM, P-value associated with the mean difference in percentage methylation; P-adjustedDM, Benjamini-Hochberg-adjusted P-value associated with the mean difference in percentage methylation.