Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Feb 27;15:29. doi: 10.1186/s13148-023-01446-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 4 — The integration of the glioma enhancer atlas in the context of c-Jun and related factors. A The density of the ChIPseq H3K27ac peak from the predicted glioma enhancer atlas (1st track) identified by Stepniak et al. TFBS motif predictions in LN18 and LN229 glioma cell lines inside enhancers and c-Jun binding sites are displayed separately (2nd track). Each putative JUN motif found in glioma enhancers is linked to JUN gene position (chr1:58,776,845–58,784,048). B Feature distribution of glioma enhancer (H3K27ac peaks). C Integration of glioma enhancers and chromatin openness in glioma cell lines and GBM specimens with TFBS for c-Jun and other bZIP proteins. Exons (rectangles) and introns (lines) are depicted as well as the gene orientation (arrows) in the UCSC gene composite track