Table 2.
Descriptive statistics of neuropsychological data
| Domain | Neuropsychological test | Subscale score |
Controla (n = 76) |
APOEε4 (n = 26) |
APP (n = 17) |
PS1 (n = 20) |
|---|---|---|---|---|---|---|
| Episode memory | AVLTa | Immediate 1 | 7.07 (2.68) | 6.86 (2.17) | 8.18 (2.13) | 7.05 (1.43) |
| Immediate 2 | 9.84 (2.67) | 10.14 (2.53) | 11.41 (1.84) | 10.53 (1.62) | ||
| Immediate 3 | 12.16 (2.25) | 11.91 (2.33) | 13.41 (1.73) | 12.32 (1.80) | ||
| Immediate total | 28.93 (6.40) | 28.86 (6.22) | 33.12 (4.73) | 29.89 (3.31) | ||
| Delayed recall | 10.87 (3.00) | 11.59 (2.65) | 13.12 (1.58)# | 11.21 (2.32) | ||
| Cued recall | 10.49 (4.30) | 10.50 (4.78) | 13.59 (2.58)** | 11.11 (3.68) | ||
| Delayed recognition | 12.73 (2.47) | 13.05 (1.62) | 14.06 (1.09) | 12.42 (3.20) | ||
| ROCFb | Figure copy | 34.97 (3.11) | 35.30 (1.61) | 35.82 (0.53) | 35.78 (0.55) | |
| Figure recall | 21.14 (7.38) | 21.14 (6.35) | 21.12 (7.22) | 21.03 (6.91) | ||
| Working memory | Digit Span | Forward | 8.57 (1.21) | 8.82 (1.22) | 9.00 (0.61) | 8.47 (1.07) |
| Backward | 5.85 (1.64) | 6.05 (1.89) | 6.24 (1.15) | 5.79 (1.65) | ||
| Language | BNTc | Initial naming | 26.25 (3.07) | 27.36 (2.40) | 27.12 (1.93) | 25.58 (2.59) |
| Cued naming | 0.64 (0.98) | 0.55 (0.96) | 0.59 (1.50) | 0.58 (0.77) | ||
| Selective naming | 2.73 (2.73) | 1.77 (1.60) | 2.35 (1.41) | 3.32 (1.97) | ||
| Visuospatial perception | TMTd A | Time (s) | 37.66 (15.70) | 36.23 (15.98) | 33.18 (17.96) | 30.36 (16.47) |
| Correct trails | 24.09 (1.26) | 23.95 (0.21) | 24.00 (0.00) | 24.05 (0.23) | ||
| Executive function | TMT B | Time (s) | 64.01 (38.89) | 64.50 (37.51) | 46.06 (17.05) | 48.74 (26.90) |
| Correct trails | 23.55 (1.62) | 23.09 (2.65) | 24.00 (0.00) | 24.05 (0.23) |
#0.017 < P < 0.1, *0.01 < P < 0.017, **0.001 < P < 0.01
aAVLT: Auditory Verbal Learning Test
bROCF: Rey-Osterrieth complex figure test
cBNT: Boston naming test
dTMT: trail making test