Table 2.

Plasma activities of ALT, AST, ALP, LDH, GGT, and levels of total protein, albumin, and total bilirubin in control and experimental rats after 10 days treatment with mancozeb, mancozeb combined with curcumin, and curcumin alone.

Parameters/treatments	Control	MZ	MZ + Cur	Cur
ALT (IU/L)	23.67 ± 1.67	41.50 ± 3.66b	23.00 ± 3.51e	23.75 ± 1.75
AST (IU/L)	46.33 ± 10.73	92.33 ± 1.67a	52.33 ± 10.91	53.00 ± 7.88
ALP (IU/L)	92.40 ± 8.07	216.30 ± 8.74c	139.00 ± 22.87e	89.00 ± 9.60
LDH (IU/L)	32.83 ± 3.11	49.00 ± 2.89b	36.25 ± 1.80d	34.07 ± 1.68
GGT (IU/L)	10.25 ± 0.72	24.75 ± 2.66c	11.74 ± 0.78f	11.33 ± 0.88
Total protein (g/L)	88.00 ± 2.65	68.75 ± 3.12a	83.25 ± 2.84d	84.25 ± 4.73
Albumin (g/L)	40.67 ± 2.03	33.33 ± 0.88a	39.67 ± 0.88d	40.00 ± 0.58
Total bilirubin (μmol/L)	6.33 ± 1.20	13.00 ± 0.41a	6.25 ± 1.65d	6.33 ± 1.45

Values are means ± SEM for 6 rats per group.

Abbreviations: MZ, mancozeb; Cur, curcumin; ALT, alanine transaminase; AST, aspartate transaminase; ALP, alkaline phosphatase; LDH, lactate dehydrogenase; and GGT, gamma glutamyl transpepdidase.

^aDenotes P < 0.05: MZ versus control.

^bDenotes P < 0.01: MZ versus control.

^cDenotes P < 0.001: MZ versus control.

^dDenotes P < 0.05: (MZ + Cur) versus MZ.

^eDenotes P < 0.01: (MZ + Cur) versus MZ.

^fDenotes P < 0.001: (MZ + Cur) versus MZ.