Fig. 5. Interactions between α-Syn and lipid liposomes in the presence of DOPAL and DOPAL + Lys C-dots. (A) The C-dots change the secondary structure of α-Syn in liposomes (60% DOPC, 25% DOPE, and 15% DOPS) as tested by CD spectra of α-Syn (10 μM) (black line), in the presence of DOPAL (300 μM) and liposomes (grey line), in the presence of DOPAL + Lys C-dots and liposomes (blue line). (B) The change in the anisotropy fluorescence of POPE/DMPG vesicles with time as tested by the TMA-DPH fluorescence marker in the presence and absence of 70 μM α-Syn in the presence of DOPAL and a combination of DOPAL + Lys C-dot. Each column represents the condition reported in the legend.