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. 2023 Jan 9;14(1):e03101-22. doi: 10.1128/mbio.03101-22

TABLE 2.

Delta variant associated polymorphisms

Polymorphism Odds ratio Fisher’s P value Corrected P valuea
Delta hospital associated
 ORF8_C25Y 10.29 P < 0.001 P < 0.001
 nsp13_A296S 2.30 0.001 0.002
 Spike_T385I 3.35 0.002 0.003
 nsp3_T1677I 2.84 0.007 0.012
 nsp6_T181I 2.61 0.012 0.017
 Spike_A222V 2.53 0.015 0.020
 nsp13_I334Vb 1.45 0.04 0.05
Delta community associated
 nsp3_T1002I 8.94 P < 0.001 P < 0.001
 ORF3_V13L 8.81 P < 0.001 P < 0.001
 N_D63G 51.05 P < 0.001 P < 0.001
 nsp12_A185V 5.40 P < 0.001 P < 0.001
 ORF7a_V71I 3.48 P < 0.001 P < 0.001
 nsp16_Q238H 2.99 P < 0.001 P < 0.001
 N_D377Y 30.55 0.001 0.001
 Spike_T638I 9.81 0.001 0.003
 nsp2_V123I 5.32 0.004 0.007
 ORF7a_T120I 10.35 0.02 0.03
a

After Benjamini-Hochberg multiple testing correction.

b

Polymorphism was significant (P < 0.05) before multiple testing correction but is no longer significant after correction.