Skip to main content
. 2023 Jan 19;97(2):e01227-22. doi: 10.1128/jvi.01227-22

FIG 9.

FIG 9

Deletion of the H240R gene attenuates ASFV pathological damage in pigs. (A) Gross scores of the tissues including the heart, liver, lung, kidney, spleen, tonsil, thymus, and six lymph nodes (inguinal lymph node, submaxillary lymph node, bronchial lymph node, mesenteric lymph node, mediastinal lymph node, and gastrohepatic lymph node) of pigs mock-challenged or challenged with 103 HAD50 of parental ASFV-WT (n = 6), 103 HAD50 of ASFV-ΔH240R (n = 6), or 105 HAD50 of ASFV-ΔH240R (n = 6) were recorded and analyzed. (B) Tissue lesions noted in the spleen, mediastinal lymph node, and tonsils of pigs inoculated with ASFV-WT (103 HAD50) or ASFV-ΔH240R (103 HAD50 or 105 HAD50). (C) Hematoxylin and eosin-stained images of heart, liver, kidney, thymus, bronchial lymph nodes, and mesenteric lymph nodes from pigs mock-challenged or challenged with ASFV-WT (103 HAD50) or ASFV-ΔH240R (103 HAD50). Scale bars = 200 μm. The sites of inflammation are magnified in the panes on the right. Scale bars = 50 μm.