TABLE 1.
Viruses used in the HIVDEP screens reported in this studya
| HIV-1 strain | Clade | Coreceptor tropism | Traits | % p24 3 dpi per biological replicate |
|---|---|---|---|---|
| LAI | B | CXCR4 | Lab-adapted | LAI: R1 = 10.57; R2 = 10.33 |
| LAI redo: R1 = 7.05; R2 = 7.5 | ||||
| LAIΔenv-VSV-G | B | NA | Lab-adapted/alternate entry mechanism | R1 = 23.93; R2 = 23.9 |
| Q23.BG505 | A | CCR5 | Primary isolate | R1 = 6.19; R2 = 6.32 |
| CH470 TF | B | CCR5 | Primary isolate/transmitted founder virus | R1 = 20.6; R2 = 22.9 |
a
LAI was used in replicate in two independent experiments to assess reproducibility of the screen (referred to as “LAI redo” in this paper). Percent infection of each biological replicate of each HIVDEP screen (as measured through flow cytometry quantification of cytoplasmic gag 3 days postinfection) is shown in the last column.