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. 2023 Jan 23;97(2):e01716-22. doi: 10.1128/jvi.01716-22

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FIG 8 — GII.4 Sydney_2012 noroviruses present epitopes from ancestral GII.4 variants. A monoclonal antibody (MAb) library developed against a wild-type GII.4 Farmington_Hills_2002 virus (MD2004-3/US/2004) indicates reactivity of MAbs, mapping to antigenic site A, against newer Sydney_2012 viruses. The columns denote wild-type and mutant VLPs. The background of the mutant VLPs is that from the wild-type RockvilleD1/US/2012 virus. The OD405 nm were normalized to the cross-reactive MAb 30A11 (1.0) and the negative control (0).