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. 2023 Jan 23;97(2):e01716-22. doi: 10.1128/jvi.01716-22

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FIG 9 — Sera from individuals challenged with a Farmington_Hills_2002 virus present HBGA-blocking activity against modern Sydney_2012 VLPs. Normalized curves are shown from sera from 6 individuals challenged with the 031693/US/2003 virus (22). Two individuals, FRN439 and FRN466, presented blocking titers that indicate closer antigenicity between the modern Sydney_2012 virus (1503F/Japan/2021) and the Farmington_Hills_2002 virus (MD2004-3/US/2004). The 1503F/Japan/2021 virus presents an antigenic site A that resembles those from Farmington_Hills_2002 virus (Table 1).