TABLE 3.
Characteristics of colorectal cancer in patients with or without DPP-4i use evaluated by IHC
| Variables | DPP-4i(+) (n = 40) | DPP-4i(−) (n = 40) | P |
|---|---|---|---|
| Tumor site | |||
| Cecum/ascending/transverse | 16 | 19 | 0.53 |
| Descending/sigmoid | 12 | 11 | |
| Rectum | 12 | 10 | |
| Histologic type | |||
| tub1/tub2/pap | 39 | 39 | >0.99 |
| muc/por | 1 | 1 | |
| pT category | |||
| t1 | 6 | 5 | 0.64 |
| t2 | 7 | 7 | |
| t3 | 22 | 21 | |
| t4 | 5 | 7 | |
| pN category | |||
| n(−) | 25 | 24 | >0.99 |
| n(+) | 15 | 16 | |
| p-stage | |||
| Ⅰ | 12 | 11 | 0.83 |
| Ⅱ | 13 | 13 | |
| Ⅲ | 15 | 16 | |
| Metformin intake | |||
| Yes | 9 | 11 | 0.80 |
| No | 31 | 29 |
NOTE: P values were analyzed with Mann–Whitney U test or Fisher tests.