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MPS-loaded Chol-NVs regulates endothelium to alleviate the lung inflammation. (A) MPS-loaded Chol-NVs inhibit the ICAM-1 expression of HUVECs challenged by TNF-α (50 ng/ml) and their quantification. (B) The protocol for lung inflammation of the mouse model. MPS-loaded Chol-NVs mitigate the lung inflammation responses. Total cells (C), neutrophils (D), total proteins (E), TNF-α (F), IL-1β (G), IL-6 (H) in BALF. Data presented as the mean ± SD, n = 3. *P < 0.05, **P < 0.01, ***P < 0.001.
