Table 4.

Time to Hemostasis and Time to Ambulation According to Closure Device Group and Randomized Treatment Group

	REG1		Bivalirudin
Variable	VCD (N=510)	Manual compression (N=489)	VCD (N=293)	Manual compression (N=280)	P value*
Time to hemostasis, min	1 (0.0–7.0)	19 (10.0–30.0)	2 (0.0–9.0)	20 (13.0–32.0)	<0.01
Time to ambulation, h	5 (4.0–8.0)	7 (5.0–13.0)	6 (4.0–9.0)	7 (5.0–15.0)	<0.01

Data are presented as median (interquartile range). REG1 indicates a combination of the factor IXa inhibitor pegnivacogin and its complementary controlling agent anivamersen; and VCD, vascular closure device.

^*Jonckheere‐Terpstra test weighted by the inverse probability of getting VCD or manual compression.