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. 2022 Dec 24;12(1):e026326. doi: 10.1161/JAHA.122.026326

Table 6.

Cox Proportional Hazard Analysis for Cardiac and All‐Cause Death Using Serial NLR and PLR Values

Univariate analysis Multivariate analysis*
HR (95% CI) P value HR (95% CI) P value
Cardiac death
High NLR and PLR on admission and at discharge 2.76 (1.38–5.54) 0.0043 2.71 (1.33–5.53) 0.0061
High NLR and PLR on admission and 1 year after discharge 3.66 (1.41–9.52) 0.0079 4.10 (1.41–11.88) 0.0094
All‐cause death
High NLR and PLR on admission and at discharge 2.56 (1.58–4.12) 0.0001 2.43 (1.46–4.06) 0.0007
High NLR and PLR on admission and 1 year after discharge 2.74 (1.36–5.53) 0.0047 2.55 (1.10–5.94) 0.0298

HR indicates hazard ratio; NLR, neutrophil‐to‐lymphocyte ratio; and PLR, platelet‐to‐lymphocyte ratio.

*

Multivariate models were adjusted for age, sex, hypertension, diabetes, coronary artery disease, hemoglobin, estimated glomerular filtration rate, and N‐terminal pro‐B‐type natriuretic peptide level. High NLR, NLR>4.5; high PLR, PLR>193.