Table 5.
Baseline and Follow‐Up Echocardiogram in 667 Patients With HCM
| Variable | Baseline | Follow‐up | P value |
|---|---|---|---|
| LVEDD, mm | 47.9±4.7 | 48.4±4.9 | 0.007 |
| LVESD, mm | 30.3±4.4 | 31.0±4.8 | <0.001 |
| LV maximal thickness, mm | 18.4±3.9 | 19.3±4.0 | <0.001 |
| IVS thickness, mm | 14.1±4.4 | 14.5±4.6 | <0.001 |
| PW thickness, mm | 10.7±2.0 | 10.6±1.8 | 0.199 |
| LVEF, % | 69.2±8.1 | 68.1±7.7 | 0.001 |
| LA volume index, mL/m2 | 36.7±14.8 | 43.7±19.6 | <0.001 |
| E velocity, m/s | 0.63±0.2 | 0.66±0.2 | <0.001 |
| E/e' | 14.7±6.0 | 15.6±6.3 | <0.001 |
| RVSP, mm Hg | 28.1±7.7 | 29.3±9.3 | 0.002 |
| MV abnormalities, n (%) | |||
| MR | 150 (22.5) | 157 (23.5) | 0.649 |
| Mild | 128 (19.2) | 129 (19.3) | |
| Moderate | 19 (2.8) | 22 (3.3) | |
| Severe | 3 (0.4) | 6 (0.9) | |
| MR progression | 67 (10.0) | ||
| MR regression | 53 (7.9) | ||
| MS | 10 (1.5) | 29 (4.3) | 0.002 |
| MS progression | 19 (2.8) | ||
| MAC | 91 (13.6) | 132 (19.8) | 0.003 |
| MAC progression | 52 (7.8) | ||
| SAM | 89 (13.3) | 91 (13.6) | 0.893 |
| MV prolapse | 16 (2.4) | 18 (2.7) | 0.728 |
Data are given as mean±SD, unless otherwise indicated. E indicates mitral inflow early diastolic filling; E/e', ratio of early diastolic mitral inflow velocity/early diastolic mitral annular tissue velocity; HCM, hypertrophic cardiomyopathy; IVS, interventricular septum; LA, left atrial; LV, left ventricular; LVEDD, LV end‐diastolic dimension; LVEF, LV ejection fraction; LVESD, LV end‐systolic dimension; MAC, mitral annular calcification; MR, mitral regurgitation; MS, mitral stenosis; MV, mitral valve; PW posterior wall; RVSP, right ventricular systolic pressure; and SAM, systolic anterior motion.