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. 2023 Mar;29(3):590–594. doi: 10.3201/eid2903.221546

Table 1. Seroprevalence of specific SARS-CoV-2 antibodies, stratified by sex, age group, and region of residence, Portugal, April 27–June 8, 2022*.

Characteristic N IgG positive, % (95% CI) S IgG positive, % (95% CI) N or S IgG positive, % (95% CI)
Overall
27.3 (25.5–29.1)
95.0 (94.2–95.7)
95.8 (95.0–96.4)
Sex p = 0.8789 p = 0.9801 p = 0.8544
M 27.4 (25.0–30.0) 95.0 (93.9–95.9) 95.7 (94.6–96.6)
F
27.1 (24.7–29.7)
95.1 (93.7–96.1)
95.8 (94.6–96.8)
Age group, y p<0.001 p<0.001 p<0.001
0–4 39.2 (32.3–46.5) 71.2 (64.4–77.2) 76.2 (69.6–81.7)
5–9 32.9 (26.6–39.9) 78.2 (71.5–83.6) 78.7 (72.1–84.1)
10–19 40.0 (35.0–45.2) 95.2 (92.5–97.0) 96.2 (93.7–97.7)
20–29 29.7 (24.8–35.2) 97.9 (95.7–99.0) 98.6 (96.5–99.5)
30–39 30.3 (25.2–36.0) 96.3 (93.4–98.0) 96.9 (94.1–98.4)
40–49 27.2 (22.3–32.7) 96.6 (93.8–98.2) 97.7 (95.3–98.9)
50–59 27.0 (22.2–32.4) 97.5 (95.0–98.8) 97.7 (95.1–98.9)
60–69 21.0 (16.7–26.0) 97.0 (94.4–98.4) 97.4 (94.8–98.7)
>70
17.3 (13.5–21.7)
96.7 (94.2–98.2)
97.2 (94.8–98.6)
Region of residence p = 0.1465 p = 0.0141 p = 0.0315
Norte 24.8 (21.6–28.3) 96.4 (94.9–97.5) 96.8 (95.3–97.8)
Centro 28.2 (24.3–32.6) 95.2 (93.0–96.7) 95.9 (93.8–97.3)
Lisboa e Vale do Tejo 29.3 (26.3–32.6) 94.2 (92.5–95.6) 95.3 (93.7–96.5)
Alentejo 25.4 (21.7–29.5) 95.3 (93.1–96.9) 96.0 (93.9–97.3)
Algarve 27.6 (23.2–32.5) 91.0 (87.6–93.5) 91.7 (88.4–94.1)
Madeira 31.0 (26.8–35.5) 94.1 (92.0–95.7) 95.6 (93.7–97.0)
Açores 24.4 (20.6–28.6) 93.7 (91.1–95.6) 95.9 (93.8–97.3)

*ISN4COVID-19 study. Weighted to match the distribution of the resident population of Portugal (Census 2021) by sex, age group, and region. p values indicate design-adjusted χ2 testing used to compare seroprevalence by sex, age group, and region. N, nucleocapsid protein; S, spike protein.