Figure 2.

HCV is detectable in spiked CSF and PBS. HCV+ blood from 2 participants, 1019 (green triangles) and 1023 (black circles), was used to spike patient matched CSF as well as PBS. Ten percent plasma was mixed with 90% CSF or 90% PBS, and an HCV viral load was performed on these spiked samples along with pure plasma and pure CSF. The limit of detection (LOD) for the HCV VL assay is shown with a dashed line.