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. 2023 Feb 28;18(2):e0282440. doi: 10.1371/journal.pone.0282440

Table 7. Multivariable analysis for variables associated with prednisolone dose in mg/m2.

Variable Number of dogs Unstandardised regression coefficient (Standard Error) P (likelihood ratio) 95% Wald confidence interval
Intercept 29.489 (1.9592) <0.001 25.649–33.329
Age (years) 1886 -0.241 (0.0712) <0.001 -0.380 –-0.101
Weight (kg) 1886 0.271 (0.0226) <0.001 0.227–0.316
Body system <0.001
    Integument 1643 Ref
    Ocular 24 2.466 (2.4648) -2.365–7.297
    Respiratory 80 1.657 (1.4181) -1.122–4.437
    Gastrointestinal 22 4.776 (2.5896) -0.299–9.852
    Neurological 61 4.556 (1.6540) 1.315–7.798
    Haematopoietic 33 11.231 (2.7617) 5.818–16.644
    Endocrine 10 -24.155 (4.2257) -32.438 –-15.873
    Musculoskeletal 7 4.453 (4.6550) -4.671–13.576
    Cardiovascular 6 3.178 (4.9032) -6.432–12.788
Indicated dose <0.001
    Immunosuppressive 80 Ref
    Physiologic 10 *
    Anti-inflammatory 1796 -11.390 (1.8598) -15.035 –-7.744

Akaike’s information criterion: 14744.678

Ref: Reference category

*Set to zero as value redundant as all dogs in the endocrine group are shared with the physiologic group