Table 1. Physicochemical characteristics of 5-FU-loaded SLNs.

Code	Precirol® ATO 5 (mg)	Poloxamer 188: Tween 80 (%w/v)	Size (nm)	PDI	Zeta Potential (mV)	%EE
SLN1	100	3%: 0.5%	327± 4.5	0.442±0.009	-9.66± 1.2	70.60%± 1.2
SLN2	100	2%: 0.5%	220.3± 3.3	0.430±0.007	-11.3± 2.1	67.72%± 2.1
SLN3	100	1.5%: 0.5%	125.3± 4.8	0.354±0.013	-20.4± 1.5	63.46%± 1.1
SLN4	100	1%: 0.5%	100.3± 2.9	0.257±0.006	-28.4± 2.6	76.08%± 2.4
SLN5	75	1%: 0.5%	84.09±1.01	0.345±0.004	-21.3± 1.2	73.40%± 3.2
SLN6	50	1%: 0.5%	76.82± 1.5	0.356±0.008	-19.4± 2.4	71.16%± 2.9

Data was presented as mean ±SD (n = 3)