Table 5.
25(OH) vitamin D levels and vitamin D deficiency prevalence among the different disease outcomes and characteristics in severe COVID-19 patients (n.36)
| 25(OH) vitamin D levels (ng/mL) | P value | ||
|---|---|---|---|
|
Life-threatening disease, yes/no |
Yes (n.17): 9.3 [6.5–18.2] | No (n.19): 13.9 [10–23.4] | 0.06 |
| NIMV, yes/no | Yes (n.16): 9.1 [6.5–16.7] | No (n.20): 14.5 [10.2–23] | 0.026 |
| ICU, yes/no | Yes (n.7): 7.3 [6.5–10.8] | No (n.29): 13.9 [9–19.4] | 0.04 |
| Death, yes/no | Yes (n.3): 13 [8–22] | No (n.33): 12.2 [8–17.6] | 0.4 |
| ALI-ARDS, yes/no | Yes (n.29): 15.9 [11.4–29] | No (n.7): 23.6 [16.3–28] | <0.001 |
| Hyperinflammation, yes/no | Yes (n.18): 10.9 [7.4–17.5] | No (n.18): 15.4 [8.2–24.2] | 0.21 |
| Vitamin D deficiency, n. (%) | |||
|---|---|---|---|
|
Life-threatening disease, yes/no |
Yes: 15 (85%) | No: 14 (73%) | 0.41 |
| NIMV, yes/no | Yes: 15 (94%) | No: 14 (70%) | 0.1 |
| ICU, yes/no | Yes: 6 (86%) | No: 23 (79%) | 0.99 |
| Death, yes/no | Yes: 1 (33.3%) | No: 28 (84%) | 0.1 |
| ALI-ARDS, yes/no | Yes: 27 (93%) | No: 2 (28%) | 0.001 |
| Hyperinflammation, yes/no | Yes: 17 (94%) | No: 12 (67%) | 0.08 |
n. number, NIMV non-invasive mechanical ventilation, ICU intensive care unit, ALI Acute Lung Injury, ARDS Acute Respiratory-Distress Syndrome
P values reported in bold are those statistically significant