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. 2022 Dec 31;64(3):100326. doi: 10.1016/j.jlr.2022.100326

Fig. 2.

Fig. 2

Liver transcriptome analyses of WT zebrafish and Ehhadh-knockout zebrafish (Ehhadh−/−). A: KEGG pathway enrichment analysis of DEG from WT and Ehhadh−/−. B: Network interaction analysis between DEG corresponding proteins. C: DEG heat map analysis related to fatty acid metabolism. D: Flow chart of Ehhadh regulating DHA synthesis through the PPARα and insulin signaling pathways. The blue arrow indicates a significant decrease in expression. DEG, differentially expressed gene; Ehhadh, enoyl-CoA hydratase/3-hydroxyacyl CoA dehydrogenase.