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. 2023 Feb 13;120(8):e2218510120. doi: 10.1073/pnas.2218510120

Fig. 1.

Fig. 1.

Response to exercise or sham intervention in mice at the early rest or early active phase. (A) Experimental schematic. Mice were exposed to sham- or maximal-exercise intervention for 60 min at ZT3 (Orange, early rest) or ZT15 (Blue, early active), and samples were collected every 4 h up to 20 h postintervention (n = 6 per group). (B–D) Expression of core clock genes Arntl and Nr1d1 following exercise intervention at early active or early rest phase in iWAT (B), eWAT (C), BAT (D). Serum NEFA (E) and TG (F) following exercise at ZT3 or ZT15. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. (G–I) Serum corticosterone (G), adrenaline (H), and noradrenaline (I) from immediate postexercise or sham intervention at the early rest (Orange) and early active phase (Blue). *Exercise effect P < 0.05. #Time effect P < 0.05. ‡Interaction effect P < 0.05.