Table 5.

Rates of changes in % per week of species observed with SEC chromatography at 40 °C.

mAb	Phase	HMWS (%/ wk)	Monomer (%/wk)	Clips (%/wk)
Z	Protein-poor	0.84 ± 0.01	−1.16 ± 0.06	0.31 ± 0.06
Z	Protein-rich	−0.01 ± 0.04	−5.08 ± 0.28	5.09 ± 0.03
H	Protein-poor	0.58 ± 0.02	−1.06 ± 0.03	0.48 ± 0.01
H	Protein-rich	−0.55 ± 0.06	−0.28 ± 0.06	0.83 ± 0.03
I	Protein-poor	0.78 ± 0.02	−1.04 ± 0.03	0.27 ± 0.01
I	Protein-rich	0.82 ± 0.03	−1.25 ± 0.05	0.33 ± 0.02