TABLE 1.

Cluster information of all performed analyses.

Brain region	BA	Peak voxel coordinates			Cluster size	T-value	p-cFWE
		x	y	z
Intrinsic connectivity contrast (ICC): Pilots > Controls
No significant results
Intrinsic connectivity contrast (ICC): Controls > Pilots
Inferior frontal gyrus, L (pars orbitalis)	BA47	−42	40	−10	68	5.80	0.031
Seed: inferior frontal gyrus, L: Pilots > Controls
No significant results
Seed: inferior frontal gyrus, L: Controls > Pilots
Superior medial gyrus, L	BA9	0	46	46	222	4.89	0.001
Seed: right parietal operculum 2: Pilots > Controls
Visual cortex (hOc3; V3), L	BA18	−32	−100	−04	143	7.31	0.014
Seed: right parietal operculum 2: Controls > Pilots
No significant results
Seed: right angular gyrus: Pilots > Controls
Angular gyrus, L	BA39	−40	−66	36	309	4.74	<0.001
Seed: right angular gyrus: Controls > Pilots
No significant results
positive correlation between ICC maps and flight hours
Temporal pole, R	BA38	34	16	−30	67	11.67	0.001
Middle frontal gyrus, R	BA9	38	48	36	57	7.17	0.005
Inferior frontal gyrus, L (pars triangularis)	BA46	−54	40	6	41	8.76	0.050
negative correlation between ICC maps and flight hours
Postcentral gyrus, L	BA4	−50	−10	24	153	11.30	<0.001
Paracentral lobule, L	BA1	−8	−30	60	95	9.73	<0.001
Precentral gyrus, R	BA6	14	−24	72	65	8.22	0.002

Significant clusters for the intrinsic connectivity contrast analysis, the seed-to-voxel analysis, and the correlation analysis with flight hours are described by the brain region label, peak voxel coordinates in MNI, space, cluster size and statistical information; BA, brodmann area; T-values are cluster-averaged; p-cFWE, is the p-value after cluster-wise family-wise error (FWE) correction. R = right, L = left.