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. 2023 Feb 15;14:1136574. doi: 10.3389/fphys.2023.1136574

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Copyright © 2023 Wang, Zhao, Bu, Liu, Li, Zhang, Zhang, Yuan, Wang, Guo and Shi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LSD alleviates LV wall thickness in TASK^−/− mice. Representative M-mode echocardiogram images of the LV from TASK^+/+ and TASK^−/− mice before and after a two-week LSD (A). Quantitative comparison of echocardiographic parameters including LV mass (B), LVAWd (C), LVPWd (D), LVEDV (E), LVESV (F), stroke volume (G), ejection fraction (H), fractional shortening (I) and E/A (J) from TASK^+/+ and TASK^−/− mice before and 2 weeks after LSD. The symbol * indicates a significant difference between TASK^+/+ and TASK^−/− using unpaired t-tests, *p < 0.05, ****p < 0.0001. The symbol # indicates a significant difference between before and after 2 weeks of LSD based on paired t-tests, #p < 0.05, ##p < 0.005.