TABLE 1.
Electrolytes/chemistries/blood gases.
| Parameter | Normal range | TASK+/+ (‾X±SE, n = 8) | TASK−/−(‾X±SE, n = 11) | p-Value |
|---|---|---|---|---|
| pH | 7.35–7.45 | 7.36 ± 0.01 | 7.38 ± 0.01 | 0.1383 |
| pCO2(mmHg) | 35–48 | 39.69 ± 1.43 | 40.05 ± 5.65 | 0.0357* |
| PO2(mmHg) | 83–108 | 110.20 ± 5.36 | 114 ± 5.14 | 0.6153 |
| cHCO3 -(mmHg) | 21–28 | 22.19 ± 0.39 | 26.75 ± 0.63 | 0.0001* |
| cTCO2(mmol/L) | 22–29 | 22.51 ± 2.88 | 28.12 ± 2.19 | 0.0008* |
| BE(b) (mmol/L) | −2∼+3 | −0.38 ± 0.28 | 0.83 ± 0.70 | 0.0003* |
| BE (ecf) (mmHg) | −2∼+3 | −2.7 ± 0.8 | 1.67 ± 0.70 | 0.0008* |
| cSO2(%) | 94–98 | 97.89 ± 0.31 | 98.13 ± 0.28 | 0.5720 |
| Na+(mmol/L) | 138–146 | 143.4 ± 0.6 | 146.4 ± 0.87 | 0.0179* |
| K+(mmol/L) | 3.5–4.5 | 3.99 ± 0.19 | 3.01 ± 0.14 | 0.0005* |
Analysis of the arterial blood gases, and electrolytes in TASK +/+ and TASK −/− mice fed normal diet. The symbol * indicates a statistically significant difference between TASK+/+ and TASK−/− mice on normal diet (unpaired t-test, p < 0.05). cSO2, oxygen saturation; cTCO2, concentration of total carbon dioxide; BE (b), base excess-blood; BE (ecf), base excess of extracellular fluid.