Table 2.

Summary of statistical relationships between the US and cancer cell nuclear size measurements from matched histological images and use of different kernel sizes. Values are reported from linear regression analyses and include the coefficient of determination (R²) and slope of the regression line. The 95% confidence interval (CI) was reported as a measure of statistical precision.

	Subject					Subject average
	1	2	3	4	5	H-scan US	B-scan US
Kernel size = 160 × 160 μm
p-value	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001
R 2	0.48	0.29	0.33	0.52	0.37	0.31	0.09
95% CI	0.45 to 0.51	0.26 to 0.32	0.29 to 0.36	0.49 to 0.56	0.34 to 0.41	0.30 to 0.33	0.08 to 0.10
Slope	2.9	3.9	3.7	3.4	3.5	3.2	2.1
95% CI	3.1	3.6 to 4.1	3.5 to 3.9	3.2 to 3.5	3.3 to 3.7	3.1 to 3.3	2.0 to 2.2
Kernel size = 320 × 320 μm
p-value	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001
R 2	0.50	0.30	0.32	0.60	0.28	0.40	0.12
95% CI	0.43 to 0.55	0.24 to 0.37	0.26 to 0.38	0.54 to 0.65	0.21 to 0.35	0.37 to 0.43	0.10 to 0.15
Slope	3.1	4.9	4.2	3.5	3.3	2.2	2.6
95% CI	2.9 to 3.4	4.3 to 5.5	3.7 to 4.7	3.2 to 3.8	2.8 to 3.8	2.1 to 2.3	2.3 to 2.8
Kernel size = 800 × 800 μm
p-value	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001	< 0.001
R 2	0.44	0.43	0.19	0.73	0.21	0.27	0.18
95% CI	0.25 to 0.60	0.26 to 0.59	0.05 to 0.36	0.58 to 0.83	0.05 to 0.40	0.19 to 0.35	0.11 to 0.26
Slope	3.3	6.8	3.1	3.7	2.7	3.0	3.3
95% CI	2.4 to 4.2	5.0 to 8.5	1.6 to 4.6	3.1 to 4.3	1.4 to 4.1	2.5 to 3.5	2.6 to 4.1