Fig. 6.
BRD4 and PI3K dual inhibitor MDP5 inhibits tumor growth more effectively than SF2523 when administered systemically into MB xenograft mice. A Animal body weight during the treatment period. B Tumor burden curve of DAOY cell generated tumors. C Representative pictures of harvested tumors. D Tumor weights (mean ± S.D., n = 5, *p < 0.05). E Tumor burden curve of HD-MB03 cell generated tumors. F Representative pictures of harvested tumors. G Tumor weights (mean ± S.D., n = 5, *p < 0.05).