Skip to main content
. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: Trends Pharmacol Sci. 2023 Jan 19;44(3):150–161. doi: 10.1016/j.tips.2022.12.006

Figure 1.

Figure 1.

Number of virtual small molecules and unique GPCR structures available over time. A) Number of unique GPCR structures available in the GPCRdb (most recent structure deposited: July 27, 2022) with different annotation details. The sum of unique protein activation states is shown in blue. The sum of unique GPCR members invariant to any annotation is shown in green. The sum of proteins solved with either a G protein or Arrestin bound is shown in orange. B) Number of Enamine REadily AccessibLe (REAL) molecules.