Forest plot of adjusted hazard ratio for association of CHIP with 30% decline in eGFR (meta-analysis of ARIC, CHS and MESA) among 1) individuals with eGFR<60ml/min/1.73m2 at baseline, 2) diabetes at baseline, 3) no diabetes at baseline and age >60 years at baseline. Adjusted for age, age-squared, sex, baseline eGFR, diabetes, and log-urine albumin to creatinine ratio (where available at baseline).CHIP = Clonal hematopoiesis of Indeterminate Potential, eGFR = estimated glomerular filtration rate.