Skip to main content
. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Environ Res. 2023 Jan 24;222:115356. doi: 10.1016/j.envres.2023.115356

Table 2.

Cross-sectional association between phthalate biomarkers and adiposity, N=1125

VAT P-value SAT
Phthalate biomarker Beta (95% CI) Beta (95% CI) P-value
MEP
  Per 1 SD −1.00 (−3.96 , 1.96) 0.51 0.65 (−3.38 , 4.68) 0.75
  ≤32.8 ref ref
  32.9 - 68.1 −1.59 (−6.85 , 3.67) 0.55 0.04 (−8.16 , 8.24) 0.99
  68.2 - 163 −1.57 (−7.32 , 4.17) 0.59 −0.95 (−9.91 , 8.02) 0.84
  ≥164 −4.74 (−11.10 , 1.62) 0.14 −0.44 (−10.37 , 9.48) 0.93
  P trend 0.17 0.89
ΣDBP
  Per 1 SD −0.77 (−3.74 , 2.20) 0.61 1.64 (−2.37 , 5.66) 0.42
  ≤0.0586 ref ref
  0.0587 - 0.116 1.59 (−3.77 , 6.95) 0.56 7.38 (−0.97 , 15.72) 0.08
  0.117 - 0.231 2.46 (−3.36 , 8.27) 0.41 5.75 (−3.31 , 14.80) 0.21
  ≥0.231 −1.20 (−7.97 , 5.57) 0.73 3.41 (−7.15 , 13.96) 0.53
  P trend 0.84 0.59
ΣDiBP
  Per 1 SD 4.02 (0.70 , 7.34) 0.02 6.93 (2.42 , 11.45) 0.003
  ≤0.0061 ref ref
  0.0062 - 0.0124 1.98 (−3.29 , 7.24) 0.46 4.32 (−3.87 , 12.50) 0.30
  0.0125 - 0.0249 3.13 (−2.74 , 9.01) 0.30 10.11 (0.97 , 19.26) 0.03
  ≥0.025 3.54 (−3.43 , 10.51) 0.32 10.00 (−0.87 , 20.88) 0.07
  P trend 0.28 0.04
MBzP
  Per 1 SD 1.57 (−1.53 , 4.67) 0.32 0.70 (−3.50 , 4.89) 0.74
  ≤6 ref ref
  6.1 - 11.8 3.73 (−1.63 , 9.08) 0.17 7.20 (−1.14 , 15.53) 0.09
  11.9 - 22 4.99 (−0.77 , 10.76) 0.09 3.46 (−5.52 , 12.43) 0.45
  ≥22.1 3.74 (−2.93 , 10.41) 0.27 1.62 (−8.77 , 12.02) 0.76
  P trend 0.24 0.91
MCPP
  Per 1 SD 1.63 (−1.38 , 4.64) 0.29 0.24 (−3.82 , 4.31) 0.91
  ≤1.7 ref ref
  1.8 - 3.1 2.88 (−2.35 , 8.11) 0.28 3.45 (−4.69 , 11.59) 0.41
  3.2 - 5.5 6.44 (0.81 , 12.07) 0.02 5.93 (−2.84 , 14.70) 0.19
  ≥5.6 6.35 (−0.32 , 13.01) 0.06 6.48 (−3.91 , 16.88) 0.22
  P trend 0.03 0.19
ΣDEHP
  Per 1 SD 3.75 (0.77 , 6.74) 0.01 4.86 (0.83 , 8.88) 0.02
  ≤0.101 ref ref
  0.102 - 0.181 4.72 (−0.54 , 9.99) 0.08 5.23 (−2.97 , 13.43) 0.21
  0.182 - 0.333 5.78 (0.21 , 11.36) 0.04 9.85 (1.18 , 18.53) 0.03
  ≥0.334 7.18 (0.77 , 13.60) 0.03 8.89 (−1.10 , 18.89) 0.08
  P trend 0.03 0.05
MCOP
  Per 1 SD 3.31 (0.48 , 6.14) 0.02 2.46 (−1.37 , 6.29) 0.21
  ≤2.1 ref ref
  2.2 - 3.6 2.66 (−2.52 , 7.84) 0.31 2.18 (−5.87 , 10.24) 0.59
  37 - 6.5 6.36 (0.70 , 12.02) 0.03 5.73 (−3.09 , 14.54) 0.20
  ≥6.6 5.15 (−0.96 , 11.25) 0.10 3.64 (−5.86 , 13.14) 0.45
  P trend 0.06 0.37
MCNP
  Per 1 SD 0.20 (−2.41 , 2.80) 0.88 −0.05 (−3.54 , 3.44) 0.98
  ≤1.6 ref ref
  1.7 - 2.7 2.57 (−2.62 , 7.77) 0.33 5.52 (−2.55 , 13.58) 0.18
  2.8 - 4.8 3.43 (−2.14 , 9.00) 0.23 6.08 (−2.56 , 14.73) 0.17
  ≥4.9 3.98 (−1.97 , 9.93) 0.19 5.14 (−4.10 , 14.37) 0.28
  P trend 0.19 0.31

Adjusted for age, creatinine, race, education, SES index, smoking status, alcohol use, daily energy intake, Healthy Eating Index score, Dietary Modification Trial arm