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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Environ Res. 2023 Jan 24;222:115356. doi: 10.1016/j.envres.2023.115356

Table 4.

Longitudinal associations between phthalate biomarkers and adiposity, adjusting for VAT/SAT, N=985

VAT SAT
Phthalate biomarker Beta (95% CI) P value Beta (95% CI) P value
MEP
  Per 1 SD −0.76 (−3.73 , 2.22) 0.62 −0.49 (−5.16 , 4.18) 0.84
  <=32.8 ref ref
  32.9 - 68.1 −2.01 (−8.95 , 4.93) 0.57 −7.85 (−18.72 , 3.02) 0.16
  68.2 - 163 0.34 (−6.91 , 7.60) 0.93 −10.95 (−22.30 , 0.41) 0.06
  >=164 1.76 (−5.61 , 9.14) 0.64 −3.12 (−14.67 , 8.43) 0.60
  P trend 0.84 0.96
ΣDBP
  Per 1 SD −1.57 (−4.61 , 1.47) 0.31 2.38 (−2.39 , 7.16) 0.33
  <=0.0586 ref ref
  0.0587 - 0.116 −1.79 (−8.68 , 5.10) 0.61 −0.18 (−11.00 , 10.64) 0.97
  0.117 - 0.231 5.45 (−1.63 , 12.53) 0.13 −2.55 (−13.69 , 8.58) 0.65
  >=0.231 0.69 (−6.65 , 8.03) 0.85 −0.13 (−11.65 , 11.40) 0.98
  P trend 0.68 0.55
ΣDiBP
  Per 1 SD 0.01 (−3.29 , 3.31) 0.99 0.28 (−4.89 , 5.45) 0.92
  <=0.0061 ref ref
  0.0062 - 0.0124 2.98 (−3.76 , 9.73) 0.39 4.46 (−6.14 , 15.06) 0.41
  0.0125 - 0.0249 7.36 (0.23 , 14.49) 0.04 8.25 (−2.93 , 19.43) 0.15
  >=0.025 4.87 (−2.66 , 12.40) 0.20 1.46 (−10.35 , 13.27) 0.81
  P trend 0.56 0.20
MBzP
  Per 1 SD 1.74 (−1.41 , 4.89) 0.28 3.73 (−1.20 , 8.67) 0.14
  <=6 ref ref
  6.1 - 11.8 0.46 (−6.40 , 7.32) 0.90 0.82 (−9.97 , 11.62) 0.88
  11.9 - 22 5.13 (−2.01 , 12.28) 0.16 2.47 (−8.78 , 13.72) 0.67
  >=22.1 8.07 (0.76 , 15.39) 0.03 3.87 (−7.64 , 15.37) 0.51
  P trend 0.12 0.12
MCPP
  Per 1 SD 1.61 (−1.49 , 4.71) 0.31 2.42 (−2.44 , 7.29) 0.33
  <=1.7 ref ref
  1.8 - 3.1 3.83 (−2.85 , 10.50) 0.26 −4.75 (−15.23 , 5.73) 0.37
  3.2 - 5.5 1.82 (−5.08 , 8.72) 0.61 −6.28 (−17.12 , 4.56) 0.26
  >=5.6 7.46 (0.11 , 14.82) 0.05 −0.77 (−12.32 , 10.77) 0.90
  P trend 0.50 0.64
ΣDEHP
  Per 1 SD 3.20 (0.15 , 6.25) 0.04 1.70 (−3.09 , 6.50) 0.49
  <=0.101 ref ref
  0.102 - 0.181 2.34 (−4.52 , 9.21) 0.50 −3.15 (−13.95 , 7.64) 0.57
  0.182 - 0.333 2.32 (−4.59 , 9.22) 0.51 −1.61 (−12.46 , 9.25) 0.77
  >=0.334 8.66 (1.40 , 15.92) 0.02 −1.22 (−12.64 , 10.20) 0.83
  P trend 0.18 0.56
MCOP
  Per 1 SD 1.41 (−1.50 , 4.33) 0.34 1.14 (−3.44 , 5.72) 0.62
  <=2.1 ref ref
  2.2 - 3.6 0.03 (−6.68 , 6.73) 0.99 −8.11 (−18.63 , 2.40) 0.13
  3.7 - 6.5 4.73 (−2.27 , 11.73) 0.19 0.18 (−10.80 , 11.16) 0.97
  >=6.6 6.79 (−0.44 , 14.03) 0.07 1.20 (−10.15 , 12.54) 0.84
  P trend 0.18 0.15
MCNP
  Per 1 SD 1.66 (−1.09 , 4.41) 0.24 1.61 (−2.71 , 5.93) 0.47
  <=1.6 ref ref
  1.7 - 2.7 6.29 (−0.36 , 12.95) 0.06 −0.02 (−10.51 , 10.46) 1.00
  2.8 - 4.8 5.95 (−1.13 , 13.04) 0.10 −0.82 (−11.98 , 10.35) 0.89
  >=4.9 8.99 (2.04 , 15.93) 0.01 2.68 (−8.25 , 13.62) 0.63
  P trend 0.11 0.28

Adjusted for age, creatinine, race, education, SES index, smoking status, alcohol use, daily energy intake, Healthy Eating Index score, Dietary Modification Trial arm