. Author manuscript; available in PMC: 2024 Mar 1.

Published in final edited form as: Osteoarthritis Cartilage. 2022 Dec 13;31(3):406–413. doi: 10.1016/j.joca.2022.12.002

Table 3.

Responsiveness (SRM, 95% CI) of Maximum and Mean Change in 3D JSW in Tibiofemoral Subregions over 24 months and Comparison with SRM for 2D JSWx

Sub- Region	SRM for Maximum Change in 3D JSW (N=341 knees/263 ppts)		p-values for differences with 2D JSWx SRM	SRM for Mean Change in 3D JSW (N=341 knees/263 ppts)		p-values for differences with 2D JSWx SRM
CMF	−1.75	(−1.91, −1.60)	< 0.001^*	−0.31	(−0.39, −0.22)	< 0.001^*
CMT	−1.73	(−1.92, −1.55)	< 0.001^*	−0.27	(−0.35, −0.18)	0.006^*
AMT	−1.14	(−1.24, −1.04)	NA	−0.06	(−0.15, 0.03)	NA
PMT	−1.60	(−1.72, −1.47)	NA	−0.36	(−0.44, −0.29)	NA
	(N=339 knees/261 ppts)			(N=339 knees/261 ppts)
CLF	−1.83	(−1.99, −1.67)	<0.001^**	−0.23	(−0.31, −0.15)	0.623^**
CLT	−1.73	(−1.97, −1.49)	<0.001^**	−0.20	(−0.29, −0.12)	0.761^**
ALT	−1.15	(−1.23, −1.06)	NA	−0.11	(−0.19, −0.02)	NA
PLT	−1.26	(−1.39, −1.12)	NA	−0.13	(−0.22, −0.02)	NA

Medial compared with JSWx 0.225 location with SRM [−0.13 (−0.21, −0.04)] on XR

^**

Lateral compared with JSWx 0.750 location with SRM [−0.15 (−0.25, −0.06)] on XR; N/A indicates no 2D location specific to the anterior or posterior tibia. Central medial and lateral femur (CMF/CLF); tibia (CMT/CLT); anterior and posterior tibia (AMT/ALT, PMT/MLT); SRM (mean change/SD of change).